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Small, dense deposits, termed Lewy bodies or Lewy neurites, stud the brains of patients with Parkinson's disease. The three sections of brain tissue shown above depict how the protein, alpha-synuclein (stained brown), packs these deposits. This finding, and others, leads many scientists to believe that alpha-synuclein plays a key role in Parkinson's disease. Researchers are now searching for ways to stop their negative actions and hopefully aid patients in the future.

1 posted on 03/09/2006 2:46:19 AM PST by texas booster
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To: texas booster
Folding@Home FAQ for new users:

What is Folding@Home?
A Stanford University project to find out how proteins fold.

Why it's important: Proteins folding wrong causes all kinds of diseases, like Alzheimer's, Parkinson's, and forms of cancer. Folding@Home uses novel computational methods and large scale distributed computing, to simulate timescales thousands to millions of times longer than previously achieved. Through Folding@home, scientists now have the horsepower to study the mechanics of protein folding. With its ability to share the workload among hundred of thousands of computers economically, Folding@home can help scientists understand how proteins snap, or don’t, into their predestined shapes — and may help to explain the origins of diseases such as Alzheimer’s and apparently unrelated diseases. We're fueling research that could end all that.

How does it work?: You download a safe, tested program (see link below) that is certified by Stanford University. It gets work from Stanford, runs calculations using your spare computer power, and sends the results back to the University.

Is it safe? Yes! Folding@Home rarely effects computer performance in any way and won't compromise your privacy in any way. It only uses the computing power you aren't using so it doesn't slow down other programs.

How do I get started folding for Team FreeRepublic?: 1.)Download the folding program from Stanford University's folding download page (see link below). Type in your desired username. 2) Type in 36120 for the team number. THIS IS VERY IMPORTANT - if you get the number wrong, you won't be folding for team FreeRepublic! 3) The third question asks, "Launch automatically at machine startup, installing this as a service?" - We recommend you answer YES. Otherwise you will have to manually start the program after every reboot.

How can my computer help? Even if he were given exclusive access to all of the world’s supercomputers, Standford still wouldn’t have as much processing power as they get from the supercluster of people’s desktop systems Folding@home relies on. Modern supercomputers are essentially a cluster of hundreds of processors linked by fast networking. But Stanford needed the power of hundreds of thousands of processors, not just hundreds.

There's no reason to not get involved! It's free, easy, and you can know you're helping every minute without lifting a finger.
2 posted on 03/09/2006 2:49:42 AM PST by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120))
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To: texas booster
You're right. If everyone with a computer would do this we would accelerate emencely the delivery of the cures for disease we'll be seeing soon because of it. I belong to the World Community Grid, a related organization to Folding@Home.

Jump on board people and let's live longer, healthier, better lives.

http://www.worldcommunitygrid.org/viewJoinNow.

4 posted on 03/09/2006 3:03:18 AM PST by TruthFactor (The Death of Nations... pornography,homosexuality,abortion)
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To: texas booster

My folding has ground to a halt. I can't seem to finish this WU since it gets up to 60-70% and then goes back to 0%. I suspect it is an issue with my ancient PC.

I'm looking to buy a new PC and I wonder if anyone could familiarize me with the differences between the Windows XP home, professional and media center versions.


8 posted on 03/09/2006 3:38:11 AM PST by Straight Vermonter (Stations of the Cross in Poetry---> http://www.wayoftears.com)
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To: texas booster

Cool. I just completed my 13th work unit last night. I love this!!


9 posted on 03/09/2006 3:45:56 AM PST by ovrtaxt (Join the FR folding team!! http://vspx27.stanford.edu/cgi-bin/main.py?qtype=teampage&teamnum=36120)
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To: texas booster
TEAM 36120 bump


11 posted on 03/09/2006 4:04:00 AM PST by Drango (A government that robs Peter to pay Paul can always depend upon the support of Paul.)
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To: texas booster
List of Updated Links
Why Fold - Watch This !!

Another Folding Clip

Folding@home Client Download

FreeRepublic.com Folder Stats

Extreme Overclockers Stats for FreeRepublic

Another Stats Page
15 posted on 03/09/2006 4:40:35 AM PST by Drango (A government that robs Peter to pay Paul can always depend upon the support of Paul.)
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To: texas booster

New thread bump.


16 posted on 03/09/2006 5:09:24 AM PST by processing please hold (Be careful of charity and kindness, lest you do more harm with open hands than with a clinched fist)
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To: texas booster; All

Free Republic Folders - A Tribute to Ronald Reagan

Date of last work unit 2006-03-09 08:29:49
Active CPUs within 50 days 981
Team Id 36120
Grand Score 2824713 (certificate)
Work Unit Count 18150 (certificate)
Team Ranking (incl. aggregate) 171 of 43166
Home Page http://www.freerepublic.com
Fast Teampage URL http://fah-web.stanford.edu/teamstats/team36120.html


Team members
Rank
(within team)
User Score WU
1 Klutz_dohanger 835552 5422
2 Malsua 149914 961
3 lrenh 108618 473
4 Texas_Booster 67307 450
5 VeniVidiVici 50231 259
6 LSimpson 46092 279
7 Kingu 41088 200
8 Andrewksu 40067 296
9 Craigon69 35535 125
10 Ken_in_Texas 32500 214
11 FRpapasmurf 31701 216
12 Senator_Bedfellow 27420 108
13 walkerk 26552 140
14 davemaher 26530 132
15 rach_FR 25795 195
16 ValorDaus 25369 196
17 TheMightyQuinn 25026 110
18 Advil000 23490 88
19 Compaq_Owner 22136 172
20 Uriah 20810 156
21 greenbo 20196 120
22 arderenne 19554 79
23 smith288 19415 123
24 dfwddr 18976 178
25 Derllak 18948 109
26 InfraRed 18935 121
27 stylin19a 18804 105
28 zeugma 18519 109
29 Dads_AMD3000 18445 64
30 mediamole 17490 159
31 Drango1 17085 109
32 Egon 16030 269
33 Bush_Democrat 15948 102
34 DocRock 15250 96
35 farsighted 14807 65
36 Chesterbelloc 14600 108
37 TChad 14480 92
38 HangThemHigh 13403 82
39 FrogMom 13370 87
40 Compaq_Owner3 12490 105
41 Mount_Athos 12223 53
42 mouser 11817 80
43 ezsmoke 11280 50
44 oblomov_1 10999 41
45 colinhester 10899 66
46 MarkeyD 10456 74
47 Happy_Babymoon 10247 60
48 ewg 9792 64
49 houeto 9171 58
50 fostendug 9120 58
51 JohninWAGL 8744 54
52 A.Hun 8570 79
53 RedWing9 8549 62
54 SilentServiceCPO 8521 49
55 Petronski 8415 59
56 Bobibutu 8406 59
57 Hawkeyes_Girl 8392 60
58 hessian 8134 55
59 Jim 8098 62
60 umbagi 8073 74
61 MathyKathy 8066 40
62 doc11355 8054 61
63 Treb 8045 67
64 FReeper_Dundee 7981 55
65 Brian_Allen 7965 48
66 sshultz460 7876 50
67 bubba_sales 7846 64
68 Thom_Pain 7805 54
69 Weasel 7565 55
70 Ladypixel 7239 32
71 Seamoth 7164 61
72 bbarr 7031 44
73 KJC1 6852 46
74 Jacy 6813 42
75 BoT 6797 148
76 T_Admin 6796 53
77 paengineer 6678 53
78 patricia_bell 6640 40
79 Freeper_Drago 6594 43
80 _MontanaDal 6527 43
81 RebelTex 6351 76
82 mombrown1 6350 39
83 Professional_Engineer 6344 47
84 VICI 6289 49
85 FRstentor 6269 42
86 HangnJudge 6267 37
87 PCBMan 6265 35
88 Hiredhand 6236 46
89 FourtySeven 6234 50
90 rodneymatlock 6224 42
91 FreeAtlanta 6213 33
92 j_tull 6193 37
93 Tonystransportation 6024 39
94 SoCalRocket 5771 36
95 evilC 5742 33
96 Steve_Wilson_1 5727 43
97 1066AD 5685 37
98 Flyer_FR 5677 39
99 holly_go_rightly 5673 30
100 Tatze 5661 35
101 vidi 5634 52
102 LynnHam 5482 48
103 Slothful1 5380 41
104 Veni 5263 53
105 idiots_will_catch 5259 41
106 hoping2help2 5252 30
107 Foldspace 5154 33
108 Linda_Geiger 5117 28
109 Mississippi_Freeper 5105 36
110 Vern_1 5020 44
111 MnJohnnie 4992 29
112 eyespysomething 4810 28
113 glockrocks 4806 36
114 ShakeNJake 4793 37
115 SC_Swamp_Fox 4785 33
116 Freeper_KOZ. 4737 27
117 Katya 4659 29
118 kacknor 4588 28
119 Route66_FreeRepublic 4573 27
120 dangermouse 4512 30
121 Mrs_1066AD 4506 29
122 Incredulous 4442 26
123 Tony1 4331 31
124 kenth 4326 37
125 SamFromLivingston 4287 27
126 Compaq_Owner_David 4265 38
127 BigBro1 4230 30
128 fzx12345 4194 30
129 freeper_krb 4162 29
130 ahayes 4054 19
131 KGJ1 3973 27
132 Swordmaker 3964 32
133 abner 3925 19
134 William_Helvig 3799 25
135 non-anonymous 3768 27
136 Jinx 3613 38
137 hoping2help 3611 20
138 GoldCountryRedneck 3565 24
139 nsa2318 3555 21
140 Cody 3421 27
141 ThirdOrder 3419 19
142 pbrown 3381 26
143 KGJ2 3348 23
144 Drachenfels 3304 24
145 Mike_Medved 3286 17
146 bpolhemus 3112 27
147 jimfree 3102 17
148 Pikus 3085 21
149 Dplowdude 2997 22
150 Camel_Joe 2972 20
151 geritol 2950 16
152 cgk 2919 26
153 Thomas_Bernardo 2918 13
154 Suzzee 2873 16
155 Clara_Lou 2845 19
156 Hoplite 2838 16
157 spunkets 2756 16
158 Tigermoth 2749 21
159 amigatec 2734 16
160 GaltMeister 2718 19
161 FReeper_Marie 2652 18
162 Clintons_Are_White_Trash 2556 13
163 susan 2548 21
164 Regina_Plumm 2451 19
165 brityank 2421 19
166 Sunshine55 2417 16
167 VAcharonD1 2319 14
168 ENDUSER_Michael 2298 16
169 feefee 2291 15
170 GL-Bartaholic 2286 19
171 David_White 2242 14
172 rrapson 2196 13
173 greedo 2177 13
174 dbender5555 2093 11
175 gl_terri 2092 14
176 Klutza_dohanger 2064 11
177 WESTPALMSENIOR 2048 13
178 Yokiepoo 2037 12
179 c505ber 2026 13
180 mastercylinder 2006 10
181 uglybiker 1898 13
182 Incorrigible 1877 12
183 paulat2 1770 13
184 OldsDontFloat 1697 8
185 Fire_on_High 1676 11
186 manwiththehands 1664 13
187 Brian_Admin 1649 12
188 Izzy_Dunne 1648 7
189 Tim_Colman 1622 7
190 ArgentCent 1548 9
191 Chris_Primavera 1543 9
192 placerville9 1539 15
193 The_Seeker_Veritas 1524 14
194 Fanfan1 1521 6
195 PureSolace 1515 6
196 GLDoug 1491 11
197 RetroSexual 1489 18
198 Zcrack 1447 9
199 In_Memory_of_DUKE 1438 6
200 Cralic 1363 10
201 ArgentCzar 1357 8
202 Rate_Determining_Step 1341 7
203 Tactical 1322 9
204 Pusterfuss 1274 9
205 AndyKaz 1267 5
206 xeniast 1249 6
207 NonValueAdded 1248 6
208 HBAR223 1243 9
209 MRadtke 1208 7
210 conoverc 1159 7
211 David_G_1 1143 9
212 MrBlueSky2005 1091 7
213 Trax_Admin 1089 8
214 Kevin_Inspiron 1088 7
215 BitDrifter 1087 9
216 ShadowSnakeX 1048 8
217 IandJ 1021 6
218 GL_DAME 937 5
219 MyMacMini 934 12
220 bgalbreath 932 16
221 Roger__Heidt 921 7
222 Jeff_Musselman 909 6
223 Cementjungle 872 7
224 fatboynic 863 5
225 Anonymous 841 6
226 Chanticleer 797 5
227 sales_don 749 5
228 Kosst_Amojan 740 6
229 TheLooseThread 729 4
230 sirtaurus 725 6
231 Tax_Government 704 5
232 Professor_Poindexter 690 4
233 DTwistedSisterS 675 9
234 Reactionary 649 4
235 SoDak 648 5
236 SlicksaDk 644 4
237 Suzy_Que 616 5
238 Where_are_my_marbles,_Nancy? 600 1
239 aaiken 600 1
240 Tami 594 4
241 Becky1 568 4
242 Big_Bobs_FTW_1 549 3
243 G_Thomas_Wilson 518 4
244 twinzmommy 516 6
245 SV 514 3
246 RIP_DUKE 480 2
247 Westlake 476 5
248 David_Griffith 453 4
249 StrictTime 443 2
250 Clintons_Are_White_Trash_2 429 2
251 MassLengthTime 404 1
252 DB5555 394 2
253 melt 394 2
254 Gary 372 2
255 Kevin 355 2
256 Big_Texan_in_Boston 354 3
257 cdgent 343 2
258 Sgt_Schultze 322 2
259 4_DUKIE_SCHMOOKIE 306 2
260 grey_whiskers 306 2
261 Vladimir_F 287 10
262 ARubin 287 2
263 unruly.human 282 2
264 desert_girl 246 2
265 dblevins 241 1
266 Clintons_Are_White_Trash_1 241 1
267 Jack_of_All_Trades 241 1
268 INFOOL7 241 1
269 auboy 241 1
270 CPQ_1700 197 2
271 MONTANADAL 187 3
272 Michael_K 182 1
273 FRpapasmurf_client 181 1
274 datajockeys-admin 172 1
275 Heil_Dad 171 3
276 ChadGore 168 4
277 Jess35 166 1
278 GL_Doug 153 1
279 IoCaster 153 1
280 Recovering_Hermit 153 1
281 MontanaBeth 153 1
282 datajockeys-lab 153 1
283 Angry_Elephant 153 1
284 unruly.human 133 3
285 Shadow_Deamon 128 1
286 BellStar 92 2
287 Pitcherfan19 48 1
288 Fanskar 48 1
289 Klurz_dohanger 46 1
290 linda_gei 46 1
291 greenbo__ 46 1
292 DocRock_2 46 1
293 Zach_Erskine 41 1
294 jarod_1 19 1
295 Cincinnatus 1 1

25 posted on 03/09/2006 8:34:26 AM PST by soccer_maniac (Do some good while browsing FR --> Join our Folding@Home Team# 36120: keyword: folding@home)
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To: texas booster

Bump in the night, bump


38 posted on 03/09/2006 6:57:40 PM PST by dfwddr (Join our Folding@Home team (Team# 36120) keyword:folding.)
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To: texas booster
You just posted a 2001 reprint from a 1997 issue of Nature. Folding@Home isn't mentioned anywhere within the article, and with good reason: It wasn't even around when this was first published. I'm afraid your headline, and your decision to place this in News, are seriously misinformed.
44 posted on 03/10/2006 6:03:39 AM PST by Caesar Soze
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