"Unless ethanol becomes more commonly accepted, no major manufacturer is going to bring an engine to market optimized for it."
You're about ten years behind the times.
Just a few vehicles available.
Dodge Caravan
2006
Ethanol
Dodge Durango
2006
Ethanol
FORD
Crown Victoria
2006
Ethanol
FORD
F-150
2006
Ethanol
Avalanche
2006
Ethanol
CHEVROLET
Impala
2006
Ethanol
Monte Carlo
2006
Ethanol
Silverado
2006
Natural Gas
Silverado
2006
Ethanol
Silverado
2006
Bi-Fuel Natural Gas
Suburban
2006
Ethanol
Tahoe
2006
Ethanol
GENERAL MOTORS
Yukon
2006
Ethanol
Yukon XL
2006
Ethanol
LINCOLN/MERCURY
Grand Marquis
2006
Ethanol
Lincoln Town Car
2006
Ethanol
Taurus
2006
Ethanol
Taurus Wagon
2006
Ethanol
Dodge Grand Caravan
2006
Ethanol
Dodge Ram Pickup
2006
Ethanol
Dodge Stratus
2006
Ethanol
My current truck is a 2006 Silverado. While I fill it almost exclusively with e85, it gets better mileage on gasoline. GM could retune the engine for alcohol, but it would then require a very high octane gasoline where ethanol wasn't available (and it still wouldn't run as well on it). There just isn't that sort of demand yet.
I used to have a 1972 Nova which we modified to run denatured alcohol (in the days before electronic ignition and fuel injection). That sucker wouldn't run at all on unleaded gasoline, but it was a rocket on ethanol.