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To: FBD

Why do we need all this?


48 posted on 03/03/2006 8:37:48 AM PST by Conservativegreatgrandma
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To: Conservativegreatgrandma; cyborg; neverdem


I think many vaccines are far riskier then most believe.

Here's a good vaccine info site:
http://www.909shot.com/
The National Vaccine Information Center (NVIC)
http://www.909shot.com/


50 posted on 03/03/2006 8:51:47 AM PST by FBD (surf's up....way up!)
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To: Conservativegreatgrandma
Why do we need all this?

That doesn't mean every vaccine has all those ingredients. With apparently all vaccines, except influenza, coming as single unit doses, I believe they also include product information sheets that you can ask for, and which contain the ingredients. Here's the first page list of ingredients in the DTaP vaccine from http://www.fda.gov/cber/label/tdapgla122905LB.pdf

BO:LX PRESCRIBING INFORMATION BOOSTRIX®
(Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed)
DESCRIPTION BOOSTRIX® (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed) (Tdap) is a noninfectious, sterile, vaccine for intramuscular administration manufactured by GlaxoSmithKline Biologicals. It contains tetanus toxoid, diphtheria toxoid, and pertussis antigens (inactivated pertussis toxin [PT] and formaldehyde-treated filamentous hemagglutinin [FHA] and pertactin [69 kiloDalton outer membrane protein]) adsorbed onto aluminum hydroxide. The antigens are the same as those in INFANRIX® (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed), but BOOSTRIX is formulated with reduced quantities of these antigens. Tetanus toxin is produced by growing Clostridium tetani in a modified Latham medium derived from bovine casein. The diphtheria toxin is produced by growing Corynebacterium diphtheriae in Fenton medium containing a bovine extract. The bovine materials used in these extracts are sourced from countries which the United States Department of Agriculture (USDA) has determined neither have nor are at risk of bovine spongiform encephalopathy (BSE). Both toxins are detoxified with formaldehyde, concentrated by ultrafiltration, and purified by precipitation, dialysis, and sterile filtration. The 3 acellular pertussis antigens (PT, FHA, and pertactin) are isolated from Bordetella pertussis culture grown in modified Stainer-Scholte liquid medium. PT and FHA are isolated from the fermentation broth; pertactin is extracted from the cells by heat treatment and flocculation. The antigens are purified in successive chromatographic and precipitation steps. PT is detoxified using glutaraldehyde and formaldehyde. FHA and pertactin are treated with formaldehyde. Each antigen is individually adsorbed onto aluminum hydroxide. All antigens are then diluted and combined to produce the final formulated vaccine. Each 0.5-mL dose is formulated to contain 2.5 Lf of diphtheria toxoid, 5 Lf of tetanus toxoid, 2.5 mcg of pertactin, 8 mcg of FHA, and 8 mcg of inactivated PT. Tetanus and diphtheria toxoid potency is determined by measuring the amount of neutralizing antitoxin in previously immunized guinea pigs. The potency of the acellular pertussis components (inactivated PT and formaldehyde-treated FHA and pertactin) is determined by enzyme-linked immunosorbent assay (ELISA) on sera from previously immunized mice. Each 0.5-mL dose also contains 4.5 mg of NaCl, aluminum adjuvant (not more than 0.39 mg aluminum by assay), ≤100 mcg of residual formaldehyde, and ≤100 mcg of polysorbate 80 (Tween 80).

1

Please pardon the lack of paragraphs. If the unit doses don't have a separate product information sheet, you can probably find it here.

http://www.fda.gov/cber/label/label.htm

70 posted on 03/03/2006 11:23:19 AM PST by neverdem (May you be in heaven a half hour before the devil knows that you're dead.)
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