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To: elli1

Well, yes. But the side-effect profile of an MAOI is gigantic, so it seems odd to me that they chose an MAOI for a new transdermal system.


21 posted on 03/02/2006 5:03:56 AM PST by Petronski (I love Cyborg!)
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To: Petronski

See my Post #23.


25 posted on 03/02/2006 5:26:24 AM PST by elli1
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To: Petronski
Here's some drug info on selegiline:

Selegiline is generally very well tolerated. Because it is metabolized to amphetamine derivatives, it is typically administered in the morning and at midday rather than in the evening to minimize the potential for insomnia. Some patients experience gastrointestinal side effects. Unusual side effects include increased liver enzymes and aggravation of peptic ulcer disease.

Selegiline

Could very well be that trans-dermal administration minimizes side effects and is easier on the tummy.

27 posted on 03/02/2006 5:39:30 AM PST by elli1
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