Re your #27 -
It seems that England was swept by two plagues during Shakesperes' lifetime.
A couple of his theaters had to be shut down to minimize the exposure between people in the audience - could that condition have been a lingering symptom of a non lethal bout of the plague?
Does anyone have a picture of the "Death Mask"?
I don't know what, if any, has been written about post-illness physical manifestations of plague survivors, but usually Mikulicz's describes swelling caused by active white blood cells and active disease.
There were supposedly people who had the germ but had no symptoms (i.e. carriers) because of a mutation in their immune systems. Interesting to wonder if they did have some physical changes that no one noticed at the time.
I suspect analysis if his bones might give us some clues but I can't see that ever happening especially since the message on his tombstone says to leave his bones alone!