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Depression gene found
News.com.au ^ | 02/26/2006 | By Clair Weaver and Andrew Chesterton

Posted on 02/25/2006 8:22:24 AM PST by oxcart

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To: oxcart

I think there are multiple types of depression. There is a "chemical depression" which appears to be long term and is helped by drugs. There is also a "behavioral depression" whose problems appear to be more psychological than physical and drugs only dull them, not help them.

I've had the chemical depression and been aided by the zoloft/paxil type medicines although I stopped them myself many years ago. I do think some of the people who are put on these drugs and then kill themselves or others were people who were not chemically depressed and the drugs only made their mood worse because they did not see themselves getting better even when drugged.

Treating both depressions the same way is like treating Type I and Type II diabetics the same way. There are similarities, yes, but the way to treat them might be totally different.

I say none of this as a doctor or a scientist. I say it only as a patient who went through hospitalization and therapy twice over my depression and observed many others while there. Medicine helped some but seemingly did nothing for others.


141 posted on 02/25/2006 11:10:06 AM PST by Tall_Texan (Hate means never having to say you're crazy.)
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To: All
This thread almost begs another thread:

There seems to be an unusually high number of FReepers who claim to be depressed in one fashion or another. Are depressed people more attracted to FR or is it just a manifestation of a greater degree of depression in the cyber world?

142 posted on 02/25/2006 11:10:06 AM PST by Melas (What!? Read or learn something? Why would anyone do that, when they can just go on being stupid)
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To: vimto
You might make the world interesting but you've got no eye for irony.

Irony is depressing. ;)

143 posted on 02/25/2006 11:11:16 AM PST by Melas (What!? Read or learn something? Why would anyone do that, when they can just go on being stupid)
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To: Melas
You were unhappy. Due to a crappy situation and took action against the situation.

The nature of clinical depression is that I could want to kill myself in the midst of perfection and paradise.

That's how I could tell there was a problem--things were great by any standard and I would lie awake each morning in a cold sweat shaking in anger and fear.

When things are crappy, and your unhappy, that's normal. When things are great and you feel like snuffing yourself out of some free-floating, nonsensical emotional pain, there is a problem.

At that point, there are two choices: you can get help or you can kill yourself.

I could've taken a pill or a bullet. I chose to take the pill. It doesn't matter at all if people criticize me for that. I'm still here. Heh!

144 posted on 02/25/2006 11:13:34 AM PST by Cogadh na Sith (There's an open road from the cradle to the tomb.)
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To: Melas

Point taken.

warm regards.


145 posted on 02/25/2006 11:13:49 AM PST by vimto
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To: VeritatisSplendor

Thanks Mrs VS. I'll check it out.


146 posted on 02/25/2006 11:27:44 AM PST by toomanygrasshoppers ("In technical terminology, he's a loon")
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To: Austin Willard Wright
Obviously, you know no one close who is beset by these devils. it is realy and cruel...
Consider yourself fortunate.
147 posted on 02/25/2006 11:28:38 AM PST by Publius6961 (Multiculturalism is the white flag of a dying country)
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To: vimto

i'm not a psychiatrist (nor a medical doctor), but you might consider seeing one and trying an anti-depressant.
there are also non-drug therapies (e.g., cognitive therapy) that could possibly help, particularly if used in combination with an anti-depressant.
however, if you see a psychiatrist, just be sure he/she rules out bipolar disorder before you take an anti-depressant, because these meds can trigger manic episodes in (undiagnosed) bipolar people.


148 posted on 02/25/2006 11:29:47 AM PST by drhogan
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To: technochick99

What's CBT?


149 posted on 02/25/2006 11:31:47 AM PST by Publius6961 (Multiculturalism is the white flag of a dying country)
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To: Cogadh na Sith
The nature of clinical depression is that I could want to kill myself in the midst of perfection and paradise.
That's an excellent way of describing it.

150 posted on 02/25/2006 11:33:03 AM PST by DallasMike
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To: DCPatriot
Do you think that it is a conscious decision to prefer to be attracted to your own sex?

Perhaps not.
But I also believe absolutely that man and his spirit and intellect allows him, if he wishes, to rise above the anomaly in beasts.

151 posted on 02/25/2006 11:34:34 AM PST by Publius6961 (Multiculturalism is the white flag of a dying country)
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To: Publius6961
CBT = Cognitive Behavioral Therapy.

Kind regards,
152 posted on 02/25/2006 11:34:46 AM PST by vimto
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To: oxcart
A real breakthrough or another way to sell pills?

As someone who has suffered depression from childhood, I can only hope it is a breakthrough.

I have gone through the therapy stuff, I tried the pills, neither were all that helpful. As I am now going through the process of menopause, I have found that I am having fewer and fewer bouts with the very deep depressions that I would experience. With me, it appears hormones had a lot to do with my depressions, although I still have depressive episodes, just not as severe.

153 posted on 02/25/2006 11:40:03 AM PST by LibertarianLiz
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To: Tall_Texan
What I am saying that is that depression is now vying to be one of the most over-diagnosed diseases, ever.
Thanks for your posts and your pains to make your point. We agree with one another here. Sometimes drugs are prescribed that relieve the symptoms when there are actually other underlying causes. These causes may not be the sufferer's fault, like past trauma, or they may be the sufferer's fault, like a guilty conscience.
Stingray: Conservative blog

StingrayConservative Christian News and Commentary


154 posted on 02/25/2006 11:40:39 AM PST by DallasMike
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To: technochick99

you might ask your doctor about possibly changing the dose or augmenting it with something else.
if none of that helps, your doctor might be able to try a different medication.


155 posted on 02/25/2006 11:41:39 AM PST by drhogan
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To: vimto
Hope you feel better. I think I have the short-short version of the short gene myself, but fortunately, SSRIs work very well. Hope one of these days your day goes a little better.
156 posted on 02/25/2006 11:44:12 AM PST by steve86 (Acerbic by nature, not nurture)
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To: Vision

it's not "all" in the genes, but genes do play an important role in the vulnerability to depression. life events can also play a role.
it doesn't mean we have no power to change our lives, anymore than the role of genes in heart disease or cancer means we should just give up.
real depression is an illness (not just a feeling); joy and laughter are not illnesses.


157 posted on 02/25/2006 11:45:15 AM PST by drhogan
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To: najida
well?
Which are you? Long or short?

Hugs, Naji!

158 posted on 02/25/2006 11:45:20 AM PST by Publius6961 (Multiculturalism is the white flag of a dying country)
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To: Dante3
I've a friend who swears by St. John's Wort.

Works for some. However, for me it definitely makes things worse, much worse, although SSRIs are highly beneficial. I'd advise caution for any of these and always try to have another person monitor your reaction.

159 posted on 02/25/2006 11:47:55 AM PST by steve86 (Acerbic by nature, not nurture)
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To: cajungirl

i think you are right. if depression followed the pattern of single-gene inheritance, that fact would be in all the psych textbooks.
also, there are other neurotransmitters besides serotonin that play a role in depression and mood, such as dopamine and norepinephrine.


160 posted on 02/25/2006 11:48:20 AM PST by drhogan
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