A few weeks back, a friend let me shoot his .50 S&W Magnum revolver. The brass case was big enough to swallow a .45 round whole. With porting, the recoil was managable (then again, we're both pretty big guys)
little guys aim low!!!
I got to shott my buddy's S&W 500, 1 round was all I could handle. It kicked like a pissed off mule. He is 6'8" 350lbs, he handles it like a pop gun