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Bird flu nightmare needs wake-up call
Scotsman.com ^ | January 28th, 2006 | Al Avlicino

Posted on 01/28/2006 1:29:23 PM PST by Termite_Commander

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To: redpoll

Yes, I agree with you about the writer's style.

It may be he's trying to be blunt and alarmist in hopes it will catch people's attention. Of course, that might just turn other people off.

Or maybe he just enjoys human suffering...

Who knows?


41 posted on 01/28/2006 5:17:32 PM PST by Termite_Commander (Warning: Cynical Right-winger Ahead)
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To: Termite_Commander
"Er, that 5% number was not scientific in any way."

No sh~t Sherlock. The attitude doesn’t make you look smarter. My question was reasonable.

"It would be virtually impossible for H5N1, the deadliest influenza strain ever seen, to mutate into a highly benign strain."

AFAIK, no one can predict the results of a mutation that makes human transmission easy. For all we know, we have little immunities to a virus like this because it isn’t easily transmitted. If we’ve never been exposed, we’ve never had to evolve past it. And whatever mutation would make it more contagious would make it look like something that our immune systems are prepared for. That’s of course just a wild guess, but AFAIK so’s the claim that the new mutated form of the virus would be deadly.

"If we're all a bunch of panic-mongering fools, and the warnings are utter nonsense, why do you trouble yourself coming in to shoot them all down? Since we're kooks, don't waste your time on us. "

You’re right, how dare I suggest that this thing might not mutate into something deadly and that there are social, political and psychological reasons pumping up our concern. What a troll I am be for intruding on your thread. Using your reasoning, maybe you shouldn’t waste your time on me. Maybe I’ll be intimidated by your condescending attitude and stop suggesting such things.

42 posted on 01/28/2006 5:23:37 PM PST by elfman2
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To: elfman2
No sh~t Sherlock. The attitude doesn’t make you look smarter. My question was reasonable.

Excuse me if I don't quite understand why you're biting my head off. I was saying not to take my number seriously, because it's not from the WHO or something. I was only explaining that I used it as an example, and not to take it as a factual figure.

AFAIK, no one can predict the results of a mutation that makes human transmission easy.

Well, we can't pin down an exact "critical" mutation, but we do have an idea of what's bad and what's not.

For all we know, we have little immunities to a virus like this because it isn’t easily transmitted.

Correct. We've never been exposed to the H5N1 strain before, so it's new to our immune systems.

If we’ve never been exposed, we’ve never had to evolve past it. And whatever mutation would make it more contagious would make it look like something that our immune systems are prepared for.

Well, it doesn't quite work that way. Just because the H1N1 virus (one we have been exposed to) had a mutation at position 267 does not mean that if H5N1 picks up that same mutation at 627 we're going to have any kind of immunity to it. It's still a new virus as far as our immune systems are concerned.

That’s of course just a wild guess, but AFAIK so’s the claim that the new mutated form of the virus would be deadly.

I don't see any possible reason why a virus would cease to kill anybody if it mutated for easy transmission between humans. Of course, I don't have a crystal ball, so I don't know for sure, but there is no way I can see that such a thing could happen. You would need hundreds of mutations on all 8 proteins of H5N1. You'd need so many significant changes that the virus probably considered H5N1 any longer because the mutations needed would probably include extensive changes on the HA and NA proteins, which the H5N1 virus is named for.

You’re right, how dare I suggest that this thing might not mutate into something deadly and that there are social, political and psychological reasons pumping up our concern. What a troll I am be for intruding on your thread. Using your reasoning, maybe you shouldn’t waste your time on me. Maybe I’ll be intimidated by your condescending attitude and stop suggesting such things.

I never said that I was 100% sure this would mutate into a pandemic strain. The author of the article I posted seems to think that, but he's not me. And yes, there are those who would benefit from saying, "A pandemic is coming." I don't think money is the motivator in this situation. My opinion, and the apparent opinion of pretty much every health organization in the world, is that we are at risk from H5N1. Maybe money does fit into that, maybe not.

If you can please drop the dripping sarcasm routine, we could have a constructive discussion instead of a shouting match.
43 posted on 01/28/2006 5:43:58 PM PST by Termite_Commander (Warning: Cynical Right-winger Ahead)
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To: Termite_Commander

Someone freepmailed me asking about the recent study on elderberries and bird flu. Here's a link in case anyon else is interested:

http://www.freerepublic.com/focus/f-news/1565907/posts
Study shows Israeli elderberry extract effective against avian flu

BTW, I admire your politeness in the face of rudeness.


44 posted on 01/28/2006 5:48:20 PM PST by little jeremiah
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To: Termite_Commander
Uh oh. Error alert.

"Well, it doesn't quite work that way. Just because the H1N1 virus (one we have been exposed to) had a mutation at position 267 does not mean that if H5N1 picks up that same mutation at 627 we're going to have any kind of immunity to it. It's still a new virus as far as our immune systems are concerned."

Change 267 to 627. Somebody needs to learn to proofread...
45 posted on 01/28/2006 5:57:15 PM PST by Termite_Commander (Warning: Cynical Right-winger Ahead)
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To: Termite_Commander

Malaria Kills Millions of People a Year,Lime tick disease Kills Millions, HIV-AIDS Kills Millions every year, SARS Kills Millions every year, Abortion Kills Millions every year, Old age Kills Millions every year, MAD COW disease Kills Millions, PBB contamination will Kill Millions, Anthrax will Kill Millions, Asbestos will Kill Millions, Mercury poisoning will Kill Millions, Cancer Kills Millions every year, Small Pox will Kill Millions, Millions will die from starvation, Millions will die from Alcohol related accidents, Millions & Millions & Millions will die of the Bird Flew !!!....................................oop's "FLU"


46 posted on 01/28/2006 6:00:25 PM PST by CheezyChesster (If your not dead already something is DEFINITELY wrong !)
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To: CheezyChesster

Thanks for the warnings. I'll go hide under my bed where it's safe.

Although Old Age might still be a problem...



And starvation.


47 posted on 01/28/2006 6:03:28 PM PST by Termite_Commander (Warning: Cynical Right-winger Ahead)
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To: Termite_Commander

TC according to Dr. Edwin Kilbourne it is likely we already have some resistance:

The fear "is very much overdone, in my opinion," said Dr. Edwin Kilbourne, an emeritus professor of immunology at New York Medical College, who has treated flu patients since the 1957 pandemic and has studied the 1918 flu. The bird flu, he said, is distantly related to earlier flus, and humans have already been exposed to them, providing some resistance.

Dr. Kilbourne and other experts also noted that when viruses become more transmissible, they almost always become less lethal. Viruses that let their hosts stay alive and pass the disease on to others, he explained, have a better chance of spreading than do strains that kill off their hosts quickly.

Moreover, he said, while much has been made of comparisons between the current avian flu and the 1918 strain, the factors that helped increase the flu's virulence in 1918 - the crowding together of millions of World War I troops in ships, barracks, trenches and hospitals - generally do not exist today for humans.

Dr. Kilbourne emphasized that medical care had improved greatly since 1918. Although some flu victims then turned blue overnight and drowned from blood, with fluid leaking into their lungs, many more died of what are now believed to be bacterial infections, which can be treated with antibiotics.

Although the death toll from that flu was high, the actual death rate was less than 5 percent.

In addition, more people now live in cities, where they have probably caught more flus, giving them immunity to later ones. "In 1918, you had a lot of farm boys getting their first contact with city folks who'd had these things," Dr. Kilbourne said.




48 posted on 01/28/2006 7:06:41 PM PST by tatown (Better to Burn Up than Fade Away...)
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To: tatown
Dr. Kilbourne has an interesting idea. What he says about passive immunity seems to go against the grain of what I've learned, but he's the expert here, not me.

However, what he says about the conditions in 1918 and the conditions today are a little off. In 1918, there were 25 million people living in those trenches, or in equally filthy conditions.

Nowadays, we have almost one billion people living in filthy conditions in the slums of China, India, and Africa, to name a few.

He mentions advances in medical care, and he's right about the fact that the improvements are there. However, in the event of a pandemic, where tens or even hundreds of millions of people would be sick, it would be extremely difficult or impossible to properly treat everybody. Heck, look at what happened with SARS. Even though there weren't many cases up in Canada, hospitals were nearly overwhelmed.

In summery, he raises good points, but I think he may be oversimplifying in a couple instances.
49 posted on 01/28/2006 7:15:00 PM PST by Termite_Commander (Warning: Cynical Right-winger Ahead)
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To: tatown
The bird flu, he said, is distantly related to earlier flus, and humans have already been exposed to them, providing some resistance.

No recognized authority on H5N1 considers that living people have any useful resistance to H5N1, except possibly for recent survivors.

There is a difference of opinion out there as to whether people born in 1918 or before and still alive might still have resistance to that flu.

The good immunology professor apparently feels that this new flu is stealing some of his thunder (and research dollars?), and so diminishes it.

Dr. Kilbourne and other experts also noted that when viruses become more transmissible, they almost always become less lethal.

Yes, little consolation to the 5 or 6% who still die.

the crowding together of millions of World War I troops in ships, barracks, trenches and hospitals - generally do not exist today for humans.

That's correct -- conditions today include much more densely crowded conditions in large western cities, especially office buildings and public transportation and sports stadiums and other venues. Maybe troops aren't more crowded, but so what? Then again, an aircraft carrier seems like a pretty optimal breeding laboratory (for the bug!) and is mobile as well.

many more died of what are now believed to be bacterial infections, which can be treated with antibiotics.

They can be treated successfully in 6 - 8 hours? Maybe if they are already hooked up to an IV. What if there are a thousand patients ahead of you? What if the first 15 patients who arrive at the hospital get the only available ventilators? (they would).

Although the death toll from that flu was high, the actual death rate was less than 5 percent.

I don't consider loss of 5% of an entire population to be insignificant.

What infinitesimal percent of the U.S. population was lost on 9/11 and how much of a stir did that cause?

50 posted on 01/28/2006 7:24:10 PM PST by steve86 (PRO-LIFE AND ANTI-GREED)
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To: Termite_Commander
"…If you can please drop the dripping sarcasm routine, we could have a constructive discussion instead of a shouting match…"

Good reply. Fair enough.

51 posted on 01/28/2006 8:31:52 PM PST by elfman2
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To: BearWash

Having been "densely crowded" on a training ship, I can speak from experience that there are NO Western cities crowded in such a manner today.


52 posted on 01/28/2006 8:38:55 PM PST by Cold Heart
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To: BearWash

"No recognized authority on H5N1 considers that living people have any useful resistance to H5N1, except possibly for recent survivors."




In any case, Kilbourne said the makeup of H5N1 itself might dampen its impact. The "N1" part of the virus refers to the classification of a certain protein on its surface. Another kind of N1 human flu virus has been widely circulating since 1977, so it's recognizable to the immune systems of many people.

When the "N" part of the flu virus didn't change between the pandemics of 1957 and 1968, the latter was a milder killer, Kilbourne noted.

So as for the current bird flu, "I am less concerned about all this business than others because I think the N1 immunity that everyone in this population has now ... may well mitigate the effects," he said.


53 posted on 01/28/2006 9:04:37 PM PST by tatown (Better to Burn Up than Fade Away...)
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To: little jeremiah
My best friend is into herbals and she's really excited about the anti-viral properties of Elderberries. She'd be happy if it dealt with the common cold or flu, not just the bird flu. From what I read, it also helps with cold-sores.
54 posted on 01/29/2006 1:04:31 AM PST by Marie (Support the Troops. Slap a hippy.)
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To: Marie

Judith Anne posted (or freepmailed me, can't remember which) a recipe she uses to make an elderberry tonic with fresh berries. I bought dried berries and adjusted the recipe ("wung it") and made my own. We've been taking it and so far this winter - no appreciable sickness. It's reputed to be a good preventive as well as shorten the length of some viral illnesses.


55 posted on 01/29/2006 7:37:23 AM PST by little jeremiah
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To: BearWash

If the bird flu becomes as easily transmissable as regular garden variety flus, it won't need barracks or trenches for people to catch it, nor filthy conditions. People catch flu just fine every year as it is. No need to squat 2 inches from someone in filth to catch flu. Just breathe in what they breathed out in a store, or touch a doorknob or pen someone touched, and then one's face.


56 posted on 01/29/2006 7:53:18 AM PST by little jeremiah
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To: Cold Heart

Hi, I worded that unclearly; my mistake.


57 posted on 01/29/2006 9:32:52 AM PST by steve86 (PRO-LIFE AND ANTI-GREED)
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To: Marie; little jeremiah

This is a recent thread on harvesting elderberry and preparing for tincture. Many other threads on the subject - use search.

You can even get involved in the "Sambucol-Wars" if you want -- is it a good thing or a bad thing to boost/suppress the immune system before/during the avian flu/cytokine storm?

http://www.curevents.com/vb/showthread.php?t=35281&highlight=elderberry


58 posted on 01/29/2006 9:46:27 AM PST by steve86 (PRO-LIFE AND ANTI-GREED)
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To: tatown
So as for the current bird flu, "I am less concerned about all this business than others because I think the N1 immunity that everyone in this population has now ... may well mitigate the effects," he said.

That's just rose-colored speculation, right? In any event, it hasn't much mitigated the effect on those thus far infected.

59 posted on 01/29/2006 9:54:34 AM PST by steve86 (PRO-LIFE AND ANTI-GREED)
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To: BearWash

OK. Now you've done it! I won't be able to get off *this* website for days! Holy Moley, there's a lot of information! What fun!


60 posted on 01/29/2006 12:08:32 PM PST by Marie (Support the Troops. Slap a hippy.)
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