According to Genesis, one.
I don't understand the notion of believing in the need to take the Bible literally when it suits one argument, and then ask for assupmtions to be made against what the Bible specifically does not say.
"And the days of Adam after he had begotten Seth were eight hundred years: and he begat sons and daughters:"
Cain, Abel, Seth, THEN daughters.
So who did Cain marry, if he married and had children BEFORE his sisters were born?
Yes, This passgae says Adam and Eve had more children after the birth of Seth.
I don't see the passage where it says there were no other children, besides Cain and Abel, before Seth. If I took your view of this verse, Adam hadn't begat anyone prior to Seth, which we know is incorrect.