With all due respect, that's a terrible comparison. Slavery existed before Jefferson, while Hamilton was directly responsible for consolidating Federal power (through advocating replacing the weaker Articles of Confederation with a strong central government in the Constitution).
Again, that in no way diminishes my enthusiasm for the man. But I believe in acknowledging the roses and the thorns.
Hamilton was perhaps the most prescient Founding Father. He established the economic foundation of this great nation, and without him the country may well have fallen soon after its birth.
He was also much more comfortable with central Federal power than I am, and was at the center of the first sexual political scandal in the United States. He was an extremely complex man, and I celebrate that complexity.
With all due respect, both "Federalism" and slavery existed before either Hamilton or Jefferson. The United States of America existed before neither man.