No, I don't agree. We Sooners and Neb are always the targets of the other Big 12 teams--they try harder to beat us than the others, no matter where we're ranked.
Nebraska, Kansas State and Texas A&M were very much down during the Oklahoma run. Colorado was also not as good as they had been. Oklahoma State wasn't very good during that time either.
Of course conference games can always come up and bite you, but when teams are weaker than they usually are the chances of getting knocked off are a lot smaller.
If Nebraska and A&M make it back to their normal strength then I'd put the Big-12 up with anyone.