Roger that. A single Harpoon would cause damage but certainly not sink this vessel. Unless you managed some spectacular secondaries and fires.
A Mk48 under the keel would do the trick nicely.
One of the best counters to this ship in the Straits of Taiwan is the Taiwanese diesel-electric boats and other unnamed undersea assets.
And how many D/E subs does Taiwan have???2 relatively modern ones,without AIP & 2 60 year old boats,which are not exactly combat fit.The Chinese are adding newer D/Es by the dozen,with vastly improved endurance & weaponry,not to mention improved ASW systems.