It will be one of the challenges that this new confederation is not anti-american. There are big benefits for western Europe if it can unite. Just think about lean administrations, a combined defense and bigger influence on its issues of interest. Of course, if America still is thinking in the old "divide et impera" categories, it will see this development as a threat. It will not not help anyway if this should be the case since your nation has only very limited influence on those issues.
Nevertheless I hope (and I am sure) that there is the will on your side of the Atlantic to solve the problems on this planet through co-operation and not with primitive pressure. It is simple realism to see that western Europe has its very own interests of course. The thing is that they are nearly congruent with the US-interests. We want to have stable conditions to sell our goods around this world. Therefore we need to be save from terror, crazy nations with nuclear arms and we need stable conditions like valid patents, working norms etc. This is the reason why America should see those changes as a great chance. It is better to speak with one working government than with the governments of Chirac, Schroeder, Verhofstadt and whoever.
BTW - if I understand your name (according to the bulla of pope Bonifatius VIII.) in FR right, you already accepted the European hegemony since the Pope is undoubted a real European. (Just joking ;-) )
Of course if the true Holy Roman Empire were to be brought back, that would be a different story...