In a book listing the 100 most influential people of all time, Newton was ranked second, right after Mohammed. Christ was third.
St Paul should've been third.
Jesus Christ without any doubt has by far the most influence in history of mankind. No one before Him had and no one after Him would have an impact that will even come close to His. Even history itself is divided before and after Him: History before Christ (BC) and History after Christ (AD, Anno Domni, year of the Lord), this is power beyond belief, power that no other person would ever have.
Actually, on second thought, St Paul should be first, since it's quite likely no one today would've ever heard of Muhammad, Newton, or Jesus were it not for St Paul. Maybe they'd be footnotes in some obscure text.