[TX Bluebonnet]

I'm familiar with Hwys 59 and 77. Where does 281 go?

[deport]

Where does 281 go?

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North from Corpus Christi to San Antonio, west of Austin and the DFW area on up to Wichita Falls and then on into OK west of Norman.

[Concho]

US 281 begins at Brownsville, and goes up near Del Rio, Wichita Falls, and on through Oklahoma, Kansas, Nebraska, South Dakota, and North Dakota, ending at Dunseith, ND, just about ten miles or so from the International Peace Gardens on the US-Canadian Border.

It is an obvious candidate for a Mexico to Canada highway.

[Tolerance Sucks Rocks]

According to my American Map Road Atlas (which uses maps by Mapquest), US 281 starts at Brownsville, TX and runs west to McAllen. Then it runs north through San Antonio and from there all the way up to Wichita Falls before it continues into Oklahoma, either on or parallel to I-44.