I wonder how this will affect the calculations of the mathematical improbability crowd.
No effect at all. They will still produce their elaborate calculations showing how impossibly improbable it is for random atoms, from random locations all over the universe, to randomly fly together and spontaneously form a DNA molecule, or a living cell, or whatever. If they knew anything about organic chemistry, they would understand that it's difficult to prevent organic molecules from forming; they've even been discovered in space. But then, if they had any exposure to actual science, they wouldn't be creationists, would they?
As you find out how each step works, they will add up to certainty.
The ID crowd is already anticipating this and have coined the phrase Intelligent Evolution. Denton has written a book about it, and Dembski might be coming on board.