You should prefer someone who can get 50 nuke votes.
They won't be able to get the 60 votes to shut off debate and bring any of these nominees up for a vote. And they don't have enough guts or votes to force a change in the rules.
I prefer Edith Jones, I'm not enthralled with Luttig but I can live with Alito. Of course I represent only myself which means what I prefer is of no consequence at all.