I agree that the costs of a filibuster must go up. However, if the intent of the McCain 11 is to prevent a nominee from reaching the floor and not simply to prevent changing the filibuster rule, then they will not support a 24/7 filibuster either.
Then effectively, the presidential appointment power has been usurped by Senator McCain and the rest of his cabal. I had thought that the Constitution invests the President with this power, and it is a plenipotential power. That is, he shares it with no one. The Senate's role is to advise and consent, exercising that role by a simple majoritarian, direct, straight up-or-down vote of the entire Senate. Since when does the power of a Senate committee trump the clear language and meaning of the Constitution?