With cubs present, No. But it might save your life. Ruger makes a model called the ALASKAN. Not lightweight, two inch barrel. But it comes in 454 Casull or 480 Ruger.Close in, it can't hurt.
Doesn't sound like a handgun.
S&W makes a .50 caliber revolver- weighs something on the order of 5lbs empty- it's so large it only holds 5 rounds- I live in bear country- only take a Winchester Defender- 3" inch magnum loads- much more likely to hit what you're aiming at unless you're an accomplished marksman with the pistol- a charging bear is no time for practice!