The flooding will be the killer. Don't you think the building itself would hold?
Let me answer my own question...
From
http://www.nola.com/hurricane/index.ssf?/washingaway/thebigone_1.html
"The wind will blow out windows and explode many homes, even those built to the existing 110-mph building-code standards. People seeking refuge from the floodwaters in high-rise buildings won't be very safe, recent research indicates, because wind speed in a hurricane gets greater with height. If the winds are 155 mph at ground level, scientists say, they may be 50 mph stronger 100 feet above street level."
Nope i dont think so, I remember during the Mississippi River flood some years ago. Houses and building where swept away with the floods, Those buildings are going to hit into other buildings.