Also, is this "heghtened" intensity of the R/F storm quadrant quantifiable? Is it, for example 10%, or 20% stronger in winds, rain?
Yes, the NE quadrant is always the worst because that's where the winds are heading the direction of land, pushing a wall of water (surge).
But, the size of this thing in area and strength, I don't think N.O. is very safe either way.
It doesn't matter at all with a storm of this magnitude. If it were a smaller storm, passing just to the east would be the worst, because the winds would shove the lake into the city from the north.
But in this case it just doesn't matter. The city is going to be uninhabitable for quite some time.