Nope. Wing spars on a low-wing airframe are in the wrong location -- bombs have to fall through them. Thus the high-wing design of the B52. However, there were (are) designs for a 747-based cruise missile platform, which uses a rotary elevator and back-drop rails. Would much rather use an 737 based airframe instead, though -- those little pocket rockets are well stressed and way overpowered.
Looking at the picture of that airplane, it appears there's plenty of room forward and aft of the wing box for bomb/missile bays. Put fuel or avionics in the wing box. I think it would make a good bomb truck. Of course the Air Force can't afford to re-engine the B-52, so no way could they afford a militarized version of a 777.