Dr. Collins 'has the faith'!
"It is not just a human/mouse comparison one can do. Eric Green at the Genome Institute has looked at this same region in many other species and, in fact, you can find this same CAPZA2 gene in everything from chimps down to zebra fishes and a lot of things in between (see Figure 4). Notice the pattern. The chimpanzee is almost 100% identical to the human, except the chimp has a deletion just before exon 2 that we do not have. Otherwise the match-up, as in most cases of human and chimp comparison, is about 98.5% to 99%. You can see that the baboon is starting to diverge. The cat and the dog and the cow all look a lot alike, and again if you look at the CAPZA2 exons, you will see that every one of those species has a nice conserved little segment there. But as you get further away to rats, mouse, chicken, two different kinds of pufferfish and then a zebra fish, about the only thing you see is the protein encoding regions, while the rest of the scattered noise goes away. Again, this is a very compelling kind of pattern in terms of what one would expect from evolution."