Fine.
The nice thing about a .45 is that you don't need expansion. It is already big enough.
My carry pistol is a Witness 10mm. First 5 rounds are 135gr XTP loaded at 6grs of W-231. Yeilds around 1720 FPS on the chrono. Follow that with 5 180gr FMJ loaded at 5.7 and another 5 200gr SP loaded at 5.9.
I still use hollow point .45's. There's less of a risk of pass-through and hitting something or someone behind the target.