Honestly, I don't know. Considering that the direction of the Supreme Court will likely be set in stone for a few decades by the end of Bush's 2nd term (2 resignations now, probably at least 1 or 2 more over the next 2 years), it might not matter.
I think the demoralization of the base that Karl Rove so masterfully energized and rolled out last year will be so great that ANY Republican candidate will have a severe disadvantage. The Bush family and the Clinton family - now such close friends - will be even closer, as Prez. Hildebeest would have Bush's SC reversal to thank for her election.
It might not matter is possibly true. It could be 1974 all over again, only lighter. So many people would stay home it would be incredible.