I think it is far more likely that Sen. Hutchison will run for the Governor of Texas in 2010 than be on any national ticket in 08. She'll win re-election to the senate and if she still wants to come back to Texas then I see a chance it will be via the Governoship. Granted Perry isn't term limited but I suspect he'll try something else after this term should he be elected again. jmo.
As an aside I don't think Hillary will be the democrat nominee in 08.
I think if the New York Republicans get off their lazy behinds they could field a candidate to beat her in the Senate race... I don't believe the media polls and have not believed them since I cast the very first vote in my life for that Ronald "Ray-guns" fellow they were so upset about...