Can I try a possible scenario.. She's given GHB at the club..goes off with the three boys. They rape her..drop her off at the hotel,..She's hysterical..ashamed..didn't want to face anybody in her group..( and again..did she have roomates..why was she in a single room) so she runs outside..stumbles over the other two clowns..they grab her, rape her, and kill her..
Yet her friends say that she got into the car willingly. That blows a big hole into your GHB theory.