The 2-engine ME-262 used Junkers Jumo 004B axial Turbojets with a thrust of 1,980lb. Its maximum speed was 870 km/h (461 mph) and a range of 1050 km (560 Mi). It used four 30 mm MK 108 cannons in the nose. Two cannons had 100 rounds and two were with 80 rounds (260 total). Rockets could also be loaded on the wings in later versions.
By comparison, The most common Mustang, the P-51D, powered by RR Merlin V-12 engine, had a max speed of 437 mph and a combat range of 950 mi (1,855 if equipped with drop tanks). Arnament was 6 .50 machineguns with 1880 rounds of ammo. It could carry 2 1,000# bombs or 10 rockets.
Yeah, the ME-262 was max 25 mph faster, but acceleration wasn't great on those early jets because they took a long time to spool up. Given that the Mustang has over 7 times the ammo, 2x or more the range - and was probably more maneuverable - I'm not so sure I wouldn't have rather been in the cockpit of a Mustang.