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Hair Stem Cells Not Just for Baldness: Mouse Whisker Stem Cells Can Develop Into Nerve Cells
WebMD ^ | March 28, 2005 | Miranda Hitti

Posted on 03/28/2005 5:54:24 PM PST by rface

March 28, 2005 -- Stem cells from hair follicles can give rise to new nerve cells, researchers report.

The finding could lead to a new, accessible source of stem cells for therapeutic uses, they report. Stem cells have drawn a lot of attention, as they can develop various kinds of cells in the right conditions.

Adult stem cells are found in various tissues in the body and can reproduce themselves into various forms of the cells found within the same type of tissue. Researchers say by harnessing a stem cell's natural ability to reproduce and replenish cells, they may be able to develop new therapies to treat disease.

In 2004, other scientists identified adult stem cells in hair follicles from mice.adult stem cells in hair follicles from mice. They mixed those stem cells with skin cells, transplanted them into hairless mice, and saw new hairs grow.

Now, the new study, also involving mice, indicates that stem cells from hair follicles can do more than make hair grow.

In this study, researchers put the stem cells into lab cultures and watched what happened over the next two months.

Within a week, the stem cells started to give rise to cells surrounding a normal hair follicle. They developed into nerve, muscle, and skin cells.

Raising the Bar

Next, the researchers went a step further. They took stem cells from the lab and transplanted them into hairless mice.

Within a week, the cells were on the move, migrating into position under the skin of the mice. After 14 days, the cells had developed into nerve cells, say the scientists.

The hair follicle stem cells are "relatively primitive," write the researchers. That widens the cells' range of possibilities, letting them make different kinds of cells, not just the type seen in hair.

The researchers included Yasuyuki Amoh of Japan's Kitasato University School of Medicine, San Diego's AntiCancer, Inc., and the University of California, San Diego. The report appears in the early online edition of Proceedings of the National Academy of Sciences.

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SOURCES: Amoh, Y. Proceedings of the National Academy of Sciences of the United States of America, early edition. News release, Proceedings of the National Academy of Sciences of the United States of America. WebMD Live Events Transcript: "Understanding Stem Cell Research." WebMD Medical News Archive: "Stem Cells Can Re-Grow Hair."


TOPICS: Culture/Society; News/Current Events
KEYWORDS: baldness; stemcells
Alternatives to embrionic stem cells are getting more common......plus the Hair Club for Men might want to put some money towards research
1 posted on 03/28/2005 5:54:26 PM PST by rface
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To: rface

Think about the most sensitive area of your body with wiskers.


2 posted on 03/28/2005 5:55:54 PM PST by cripplecreek (I'm apathetic but really don't care.)
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To: rface

Hey Jim, nice hair implants, they look just like your own.

Thanks Bob, my wife likes it , too. Hey, lets go get some cheese!


3 posted on 03/28/2005 5:57:01 PM PST by pipecorp ('E must be the king. Why? 'E ain't got sh@t all over 'im.)
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To: rface

So that's where the termed "hairbrained" arises.


4 posted on 03/28/2005 5:57:16 PM PST by Fitzcarraldo
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To: rface
"...Retrodifferentiation is a process during which mature, specialised cells can revert back to a more primitive, immature cell stage. These retrodifferentiated stem cells are then capable of redifferentiating into a variety of cell types. Therefore, the process itself has the potential to reconstitute an entire human tissue such as blood, neurones, muscle etc..."

\ http://www.tristemcorp.com/technology01.htm

5 posted on 03/28/2005 5:59:37 PM PST by Fitzcarraldo
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To: rface
The hair follicle stem cells are "relatively primitive"

Hmmmm ... do I want baldness or hair like Don King?  Tuff choice there.

6 posted on 03/28/2005 6:00:47 PM PST by usgator
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To: Fitzcarraldo

Couldn't Robin Williams donate some of his body hair?


7 posted on 03/28/2005 6:02:41 PM PST by MasterBetty
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To: cripplecreek

Somehow I can imagine hubby trying to get my poor hairless (pet) rattie dragged in for a new "designer fur coat". Considering his recent tendency to nod off with nose and paws in the food bowl, and as often as he gets sloppy human foods as treats, he'd end up one poor messy and very bewildered rattie.


8 posted on 03/28/2005 6:08:10 PM PST by Fire_on_High (I am so proud of what we were...)
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To: Fitzcarraldo

9 posted on 03/28/2005 6:11:16 PM PST by rface ("...the most schizoid freeper I've ever seen" - Ashland, Missouri)
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To: pipecorp

LMAO!!!


10 posted on 03/28/2005 6:11:31 PM PST by cmsgop ( Don't Forget to check out Bea Arthur in the "Menopause Monologues"  coming on NBC this fall)
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To: rface

If embryonic stem cells were found to cure baldness, abortion would be mandatory....


11 posted on 03/28/2005 6:31:14 PM PST by AntiGuv (™)
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