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To: MHGinTN

Adult stem cells are great for most clinical practices but they tell us precious little about most complex diseases. Studying an adult stem cell is like trying to decipher the history of Germany by looking at its automobiles. We'll need more than a few cells to solve the problem.

I am currently doing research in this field. I'm not much a credible source being that my one and only project is far from complete. It may be possible to generate a computer graphical model for most stages of cell growth, from as early as the blastula stage (perhaps earlier). Unfortunately this doesn’t work all that well as it stands, the instruments are not very accurate and many of them don't have integrated screening. Although it would be extremely difficult to map out all the differential markers and cytokines as they occur in a developing human, we may be able to predict and demarcate them using a precise mathematical formula. It may end up being a type of equilibrium matrix equation. To give you an idea of what I have seen so far, we can locate such things as the contact surfaces of the ECM (Extra cellular matrix), integrins, E-cadherin in Epithelial cells, detect the secretion of protease (causes the breakdown of the basal membrane), find patterns in collagen bindings, and a few dozen other things.

The problem is that we can’t relate many of these external activities to each other or relate external activities to internal activities, we have to choose what to look for: the formulas used have very similar experimental roles to that of the standard wave/particle model of quantum mechanics only with more definitive variables. I am struggling with this immensely but what harm can it do to try? If this emerges soon, the use of embryonic stem cells would be rendered completely unnessecary and this otherwise expensive procedure would become accessible to all scientists. This may be a shot in the dark but those patients aren't getting any younger.


27 posted on 04/12/2005 8:55:09 PM PDT by Gava
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To: Gava

Thank you for the post. Have scientists come to accept that form and function must coordinate/interact in order for a being to grow to full scale?


28 posted on 04/12/2005 9:27:30 PM PDT by MHGinTN (If you can read this, you've had life support from someone. Promote life support for others.)
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