I for one am.
But not when it comes to the fundamental God-given, unalienable rights to life and liberty.
That's why we have a Bill of Rights.
No state has the right to abrogate those rights in any way, ever.
So am I. But states (such as Southern states like Florida) don't have the right to keep black kids from going to public schools, they don't have the right to take people's property in eminent domain without paying them -- and they don't have the right to order the death of disabled people on flimsy evidence of "intent" that doesn't meet due process standards under the federal constitution. In short, there are times when the feds have to step in, to protect rights under the federal constitution.