The evolution of a super-HIV bug was
predictable. I recall reading a study some time ago that compared virulence in an African region, American homosexuals, and American IV drug abusers. In Africa with relatively few opportunities for infection, the HIV strain was relatively low in virulence, as a result of evolutionary pressure not to kill off the host too quickly, among homosexuals the virulence was higher, and among IV drug abusers, with the needle being a more efficient transmission agent; virulence was highest.