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Ear-splitting discovery rocks mammal identity [Evolution, platypus]
news@nature.com ^ | 10 February 2005 | Roxanne Khamsi

Posted on 02/11/2005 6:49:09 AM PST by PatrickHenry

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To: Oberon

The trouble with the standard you propose is how will you know when a mutation has occurred, even if you are watching for it? Why must the first person who exhibits a new trait be the same person as the first person who inherits a mutation? Many mutated genes are recessive, and their effects may not show up for hundreds or thousands of years after the mutation occurs. The only way that a mutation which is recessive would show up would be after there has been sufficient inbreeding in the population to make a heterozygous recessive individual a reasonable possibility. In other organisms, this is much less problematic than in humans, since humans have laws that prevent inbreeding, at least for several generations.


101 posted on 02/11/2005 10:53:24 AM PST by stremba
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To: stremba

That's like saying being born without eyes is an advantage because it prevents myopia.


102 posted on 02/11/2005 10:55:54 AM PST by Dataman
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To: animoveritas
I guess substantive critiques would be a bit much to expect.
103 posted on 02/11/2005 10:56:20 AM PST by general_re ("Frantic orthodoxy is never rooted in faith, but in doubt." - Reinhold Niebuhr)
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To: Dataman

No, if malaria is the primary cause of premature death in a human population in a given environment (premature death = death occurring before reproduction), then a mutation that causes premature death in homozygous individuals, but prevents premature death iin heterozygous individuals would be beneficial if the mutated allele were present in the proper frequency. Ie. common enough to make it likely that an individual would have one copy of the allele, but not so common that the individual would be likely to have two copies. Again, what is beneficial depends on environmental factors. A beneficial trait in one environment might be neutral or harmful in a different one.


104 posted on 02/11/2005 11:00:36 AM PST by stremba
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To: stremba
The trouble with the standard you propose is how will you know when a mutation has occurred, even if you are watching for it?

I'm not really proposing a standard. I'm just wondering if we've ever actually caught evolution in the act in humans. If we haven't, that doesn't mean it's wrong. You know, the old "lack of evidence" vs. "evidence of lack" thing.

105 posted on 02/11/2005 11:01:29 AM PST by Oberon (What does it take to make government shrink?)
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To: stremba

All of which begs the question, for what possible purpose would a designer give a human population a gene which is lethal in homozygous individuals? Why would there be any lethal genes at all if humans were designed? I have read that all humans have several hundred genes that are potentially lethal in homozygous individuals. (sorry I can't remember where I saw this so I can't provide a source) Why would a designer put them there?


106 posted on 02/11/2005 11:03:43 AM PST by stremba
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To: Oberon

Whether we've seen evolution in humans is a different matter from detecting a new mutation. Evolution is the variation over time of allele frequencies in a population of organisms. I don't know whether any real studies of allele frequencies in humans have ever been done or not, but now that we can sequence genomes, it should be easier to detect a shift in allele frequencies. Previous to the ability to do genetic sequencing, only phenotypes, not genotypes would have been determinable, so I'm not sure if it would be possible to conclusively observe evolution in a human population, although I would guess that a study of the relative frequency of certain phenotypes would enable scientist to say something about genotype frequencies.


107 posted on 02/11/2005 11:07:34 AM PST by stremba
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To: Michael_Michaelangelo
Most problems of the spine and neck are due to neglect or an injury from a traumatic event. Spines don't just become misaligned or damaged from a walk in the park, you know.Most problems of the spine and neck are due to neglect or an injury from a traumatic event. Spines don't just become misaligned or damaged from a walk in the park, you know.

Sure. My point was that quadrupeds don't have the same problems - it's not like they are any less susceptible to injury than we are...
108 posted on 02/11/2005 11:15:28 AM PST by Stone Mountain
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To: Elsie

"I want to know why homo sapiens was SO much better at survival no Neanderthal are still around..."

Cro-Magnon ate him. :}


109 posted on 02/11/2005 11:34:43 AM PST by furball4paws ("These are Microbes."... "You have crobes?" BC)
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To: Oberon

"I would think Victoria was a bit young to be responsible for the hemophilia in the Romanovs...but of course I could be wrong.

More to the point, hemophilia isn't a useful adaptation. It doesn't contribute to survival. (I know that you weren't claiming it was; you were making another, quite valid point.) All of the mutations I've ever heard of in humans are actually detriments to survival, causing conditions like cystic fibrosis, hemophilia, beta thalassemia, or Down syndrome. When was the last positive, advantageous mutation in humans? Shouldn't there have been one in recorded history?"

The case against Victoria is well established - she was queen for something like 70 years and had a large family. One of her daughters is responsible for passing that gene around, including to the Romanov's.

Those genetic diseases you mention are, yes, not good. BTW because we keep these people alive longer that they would have survived 1000 years ago, we not only keep those genes in our pool, but actually increase their frequencies.

Would you actually see an advantageous gene if it was in front of you? But look at some simpler things. Why are most native peoples of the tropics dark skinned? The only native blond haired, blue eyed populations are northern latitude. Is that a coincidence? Black people from Africa that are heterozygous sickle cell have increased malaria resistance. Is this going somewhere? It is well known, but not hyped, that people with higher IQ's tend to have children with higher IQ's. I think that is as good an example as one can find.

If we allowed eugenics, we might pull some of these "advantageous" genes out so they would be more visible (please do not accuse me of advocating eugenics).

What I am saying is that these "advantageous" genes are there, but not obvious. Since we so readily mix worldwide and we interfere with the natural course in our own evolution by keeping people alive that in a wild state would be quickly weeded out, it seems to me that we are doomed to be a dead end species.


110 posted on 02/11/2005 11:58:31 AM PST by furball4paws ("These are Microbes."... "You have crobes?" BC)
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To: Youngblood
 
The inevitable knee-jerk response from the holy warriors is that if you deny the literal historical truth of Noah's Flood and the week-long creation event in Genesis, then the Bible canot be considered God's word.
 
Well, this HW does NOT need a week six-day creation OR a flood to choose between the two views.  If the E's insist that ONE creature is not sufficient to transmit mutated changes but a POPULATION is, then I have to go with the Bible.
 
 
Unfortunately, most Christians 'believe' Evolution because they do NOT know what their Bible says.  If, as they say, they 'believe' the words of Jesus and then of the New Testement writers, they have to decide what the following verses mean:
 
Romans 5:12-21
 12.  Therefore, just as sin entered the world through one man, and death through sin, and in this way death came to all men, because all sinned--
 13.  for before the law was given, sin was in the world. But sin is not taken into account when there is no law.
 14.  Nevertheless, death reigned from the time of Adam to the time of Moses, even over those who did not sin by breaking a command, as did Adam, who was a pattern of the one to come.
 15.  But the gift is not like the trespass. For if the many died by the trespass of the one man, how much more did God's grace and the gift that came by the grace of the one man, Jesus Christ, overflow to the many!
 16.  Again, the gift of God is not like the result of the one man's sin: The judgment followed one sin and brought condemnation, but the gift followed many trespasses and brought justification.
 17.  For if, by the trespass of the one man, death reigned through that one man, how much more will those who receive God's abundant provision of grace and of the gift of righteousness reign in life through the one man, Jesus Christ.
 18.  Consequently, just as the result of one trespass was condemnation for all men, so also the result of one act of righteousness was justification that brings life for all men.
 19.  For just as through the disobedience of the one man, the many were made sinners, so also through the obedience of the one man the many will be made righteous.
 20.  The law was added so that the trespass might increase. But where sin increased, grace increased all the more,
 21.  so that, just as sin reigned in death, so also grace might reign through righteousness to bring eternal life through Jesus Christ our Lord.
 
 
 
If there were  no one man, that means SIN did NOT enter the World thru him.
 
If Adam was NOT the one man, that means SPIRITUAL DEATH did not come thru him.
 
If SIN did NOT enter the World thru the one man, that means Jesus does not save from SIN.
 
 
Are we to believe that the one man is symbolic?  Does that mean Jesus is symbolic as well?
 
 
The Theory of Evolution states that there WAS no one man, but a wide population that managed to inherit that last mutated gene that makes MEN different from APES.
 
 
 

111 posted on 02/11/2005 12:04:08 PM PST by Elsie (Heck is where people, who don't believe in Gosh, think they are not going....)
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To: furball4paws

and now we have NAMBLA........


112 posted on 02/11/2005 12:05:50 PM PST by Elsie (Heck is where people, who don't believe in Gosh, think they are not going....)
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To: Stone Mountain

A lot of our problems are due to aging. Most quadrapeds don't live very long. How much this impacts what you guys are saying, I'm not sure.


113 posted on 02/11/2005 12:06:42 PM PST by furball4paws ("These are Microbes."... "You have crobes?" BC)
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To: Elsie

I'm sorry, Elsie, NAMBLA ain't in my lexicon.


114 posted on 02/11/2005 12:12:08 PM PST by furball4paws ("These are Microbes."... "You have crobes?" BC)
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To: Oberon
When was the last positive, advantageous mutation in humans? Shouldn't there have been one in recorded history?

Here's one discovered in the last few years: Gene mutation makes baby super strong

115 posted on 02/11/2005 12:12:30 PM PST by Modernman (What is moral is what you feel good after. - Ernest Hemingway)
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To: general_re
Break the Markov chain...and we can talk. Until then it's just the same tired empiricism stuggling with the outliers.

Cheers!

116 posted on 02/11/2005 12:41:22 PM PST by animoveritas (Dispersit superbos mente cordis sui.)
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To: Modernman
When was the last positive, advantageous mutation in humans? Shouldn't there have been one in recorded history? Here's one discovered in the last few years: Gene mutation makes baby super strong

Hard to guess if that's really an advantageous mutation or not.

117 posted on 02/11/2005 12:50:20 PM PST by donh
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To: donh
When was the last positive, advantageous mutation in humans?

I've heard rumors that some of our blood types are turning out to be rather recent, and are speculated to have evolved to enable us to deal with differing dietary regimes that have emerged with the advent of husbandry and farming.

118 posted on 02/11/2005 12:54:19 PM PST by donh
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To: Oberon
I would think Victoria was a bit young to be responsible for the hemophilia in the Romanovs...but of course I could be wrong.

Alexandra Feodorovna was a granddaughter of Queen Victoria.

119 posted on 02/11/2005 12:55:53 PM PST by dread78645 (Truth is always the right answer)
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To: Elsie
What about the Pope? Does he not know his Bible?

And why would Adam being symbolic render Jesus symbolic too? Is the message of the Bible, for you, a house of cards that will collapse if the creation story is an allegory like all the other creation stories across the world? Most Christians seem to be doing just fine reconciling the Bible and reality of God with an ancient earth and universe.

120 posted on 02/11/2005 1:02:51 PM PST by Youngblood
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