Not sure where you are going with the mol question, nor its relevance. Here's a corollary that might speed the process:
Given about 1078atoms in the universe, a generous estimate of 1055 atoms composing earth, and focusing on fluid dynamics of the boundary layer of lithosphere - atmosphere, what are the numbers for the critical organic builders C and H?
We are talking on the order of about 1045 hydrogen atoms and 1044 carbon atoms. Both estimates >> Avogadros constant.
Recall that we are working with a large sphere, and very small things. When you consider it all, turns out that the average density is 10-3 Angstrom-3 for H and 10-4 Angstrom-3 for C. This means an average separation of about 3000 angstroms (quite a chasm) between the critical organic atoms C and H. Since most primordial investigators propose the stable molecules H2O, H2, CH4, and CO2 as the most common sources of H and C, thus the distances are probably even larger by maybe an order of magnitude or two.