[js1138]

Results Among children and adults with sickle cell anemia (homozygous for sickle hemoglobin), the median age at death was 42 years for males and 48 years for females. Among those with sickle cell-hemoglobin C disease, the median age at death was 60 years for males and 68 years for females.

[shubi]

The differential in mortality rates without malaria present is not too pertinent to the discussion. The graph of mortality in malarial areas showed a better survival rate among hybrid sickle cell allele genotypes.

This difference, however small, will result in increase presence of the sickle cell allele in the population over time. This is evolution.