Is that where Clark Griswold fell asleep at the wheel and careened down the ramp off the interstate only to wake up at the last second and avoid killing everyone? And then as he's getting directions from some locals on how to get back on the interstate, the rest of the gang is stripping their hubcaps and spray-painting "Honky Lips" on the side of the car...
Funny scene, it's too bad I can't stand Chevy Chase...
No, I think given the direction his car went he ended up in North St. Louis, which is even worse than East St. Louis. East St. Louis is just where North St. Louisans dump their victims...
Actually that scene was in St. Louis. They were coming from the east, headed west for California. They cross the bridge and you can see the Arch ahead. There are some pretty rough areas just blocks from downtown that that could have happened in.