Minimum system requirements for Windows AntiSpyware (Beta):
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Microsoft Internet Explorer 6.0 or higher
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A 300 MHz or faster processor with at least 64 MB of RAM
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Microsoft Windows 2000, Windows XP, or Windows Server™ 2003
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At least 10 MB of available free space on your hard disk
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Internet access with at least a 28.8 Kbps connection to use SpyNet™
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Looks like I'll be sticking to Spybot and Ad-Aware. Neither of them is as bloated or as picky about hardware.
Spybot S & D and Adaware don't prevent spyware/adware/malware from loading in the first place. They only remove the crap once its infected your system.