".....Folks taking daily aspirin should take it at least one hour before taking any NSAIDs."
My understanding was that the anti-platelet interference was ONLY for ibuprofen......and that other NSAIDS were ok in this regard......I STILL think that the paper I read at the time was in the Feb 15, 02 NEJM, despite the piece I posted above.
Anyway, the ibu and napro weren't very effective, so I will just quit it.....I had a ticker-clot in 99, so I will never quit the asa.
LANCET.....Feb 15, 2003 (so much for memory, LOL)
Thomas M. MacDonald, M.D., medicines monitoring unit, department of clinical pharmacology and therapeutics, Ninewells Hospital and Medical School, University of Dundee, Scotland; Garrett FitzGerald, M.D., chairman, pharmacology department, University of Pennsylvania, Philadelphia; Feb. 15, 2003, The Lancet
Study Warns of Mixing Ibuprofen with Aspirin
Painkiller combo may spell trouble for heart patients
http://www.hon.ch/News/HSN/511778.html
During the 1990s a hematologist told me that all the NSAIDS reversibly inhibit platelet aggregation. Only aspirin irreversibly inhibits platelet aggregation. Now this with multiple doses of ibuprofen and the effectiveness of aspirin being decreased. IIRC, about twenty percent of folks are aspirin resistant with respect to its cardioprotective effects.