True. In some cases, such as the origins of life and the universe, we reach the outer limits of science and enter the realm of metaphysics. We also may engage in conflicting theories about the nature of knowledge.
And evolution has what exactly to do with the origins of life and the universe? It has no more to do with the origins of life and the universe than meteorology has to do with the origins of the atmosphere and the water vapor in it. Again, let's at least debate the same ideas.