[DoorGunner]

Their only real benefit is that they don't cause upset stomachs...

A better, more accurate, statement would be:

"They do not cause or aggravate bleeding ulcers, as do NSAIDS."

Hope that helps.

DG

 

 

[neverdem]

Actually folks still suffered bleeding ulcers with Cox-2 inhibitors. Their selling point was that they reduced the incidence of major GI bleeds from about 25% in folks still taking older NSAIDs to about 20%, IIRC. That's still a lot of emergency transfusions, emergency procedures and traditional open surgery avoided.