He's sniffing paint thinner.
LOL, at the very least.
A suggestion like this is so far beyond the pale. If it's not LSD, mescaline, magic mushrooms, or some other psychotropic then there must be something organically going on between the man's ears. On top of the phone sex accusation (highly believable, by the way) O'Reilly has effectively made a rubber room reservation with Travelocity.