I think the difference between running a business and being elected to an office is having people listen to you or doing what they damn well please, until you convince them otherwise. Is an elected office a Human Resources-style job?
Those HR gals are clueless about your jobs and throw little parties at exactly the wrong time for the successful completion of my project that I spend 10 hours a day getting to that point.
There are plenty of potentially good senate candidates here in California. But I think so many people have bought into the notion that Republicans can't win here anymore (other than a big celebrity like Arnold), that it discourages them from giving it a try.