And the ramifications of Iran as a Nuclear Power would only further complicate the geopolitics of the entire planet.
Regarding the ramifications or Iran becoming a nuclear power, it seems like if Iran (or any radical Islamic country) becomes nuclear, the possibility exists that they will allow terrorists to use a nuke, possibly on us.
I imagine these kind of thoughts were part of Bush's motivation for regime change in Iraq.
Of course I realize that the US had plans to use suitcase nukes on Russia, and they on us, most likely, so in a sense, this kind of thing is not entirely new.