Going back that far, the odds are very good that most families living in the U.S. since the 19th century are related.
Not me! My folks (both sides) arrived here from different parts of Europe in the late 1800's. So I aint responsible for slavery, neither!
It doesn't matter. If your family is white, and they arrived before 1900, they are probably related to Bush and Kerry. Geneology is an interesting little exercise in geometric progression.