Don't disagree, you'll be banished to the cornfield. (Apologies to Rod Serling)
Researchers find clues about how antibodies specialize
From the article:
"The AID-RPA interaction must be regulated to bring about the specificity of the mutation," Chaudhuri says. "If this regulation is impaired for some reason, then the B cell would incur a lot of random mutations and that might lead to tumors."