I'm pretty concerned about Orlando as well. One sister lives in Windermere, and the parents and other family live in Clermont. I spoke with the parents yesterday afternoon, and they were prepared as far as food and water are concerned. Home is recent construction, with Florida's stricter hurricane-resistant building codes. Should be OK, but I'm going to contact them in the daylight hours to be sure.
They should be fine in a newly constructed home...esp. with current FL building codes. The highest wind gust I saw in Orlando was 105mph...and a well constructed home should weather that fine...but could have roof damage. I imagine we will see a lot of damage in Orlando to signs, trees, some roofs, and older or not-well constructed buildings.