Your screen name notwithstanding, the depressurization scene in Goldfinger was fiction.
It was also inaccurate.
Modern airliners can lose as many as four windows and keep flying relatively normally.
OK, substitute a crowded aircraft.
It's safe for Air Marshals to fire on aircraft because they use those Glock 9mm pea-shooters, not a massively powerful handgun like my Walther PPK (snicker)...