Keyes has been drafted by the party. He's the nominee, without even seeking to be. He has very little to gain from it, and is very much the underdog. If he drops out now, he would hurt more than help.
There's no comparison.
"I deeply resent the destruction of federalism represented by Hillary Clinton's willingness go into a state she doesn't even live in and pretend to represent people there, so I certainly wouldn't imitate it." -- Alan Keyes, 2000
He plans on going into a state that he doesn't even live in and pretend to represent the people there. He is imitating Clinton. He is destroying the federalist principles that he pretended to revere.