Probably. But she can counter with her support of the death penalty, etc. I think if the voters got a message that she has FAILED them a la Davis, she'd be toast.
That won't work because people don't expect a senator to run anything. She cannot be blamed for the situation in California, as Davis could.
The key is to portray Boxer, quite accurately, as out of step with normal values and irresponsible on national security.