[Caesar Soze]

Use something like Thunderbird, and you won't spend millions of hours deleting spam. At most, a few minutes a day reading headers in your junk box to make sure the 'bird didn't filter out some real mail by mistake.

http://www.mozilla.org/products/thunderbird/

[Yaelle]

Use something like Thunderbird

This is what I do. I have set it so that only those in my address book can get into my inbox, and the spam stays in the junk file. Yes, I have to whiz through it briefly each day to catch any decent newcomers, but it does keep my inbox down to wanted email only.